The nport component that is used to include S-parameter files in a simulation has been improved very much in MMSIM 12.1 with respect to earlier releases. However, in its current state, it unfortunately cannot be used in a pss analysis (see the comments at the end of http://www.cadence.com/Community/blogs/rf/archive/2012/11/19/spectre-rf-mmsim-12-1-preview-of-coming-attractions.aspx ).
It is currently not clear if there is sufficient demand from Cadence customers to implement support for the pss analysis into the nport component in the upcoming MMSIM 13.1 release. So, if you would like to use S-parameter files in a pss analysis in the near future, you might want to ask Cadence support to file a duplicate of CCR 1042280 on your behalf.
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Nport Component (S-Parameter Files) in PSS Analysis
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